Valacyclovir belongs to the class of medications known as antivirals. It is used to treat a viral infection affecting the skin known as shingles (herpes zoster). It is also used to treat cold sores, and to treat and prevent recurrences of genital herpes. It works by interfering with the way the virus reproduces. Valacyclovir works by stopping the virus from multiplying and spreading to nearby healthy cells. It does not cure shingles, cold sores, or genital herpes, but it does help the sores to heal more quickly, and it relieves pain and discomfort. When used to prevent recurrences of herpes, it also reduces the risk of transmission (spreading) of the infection to others. Hi Pat, I checked valacyclovir (valtrex) against four drugs commonly used in treating breast cancer for drug interactions. The drugs are Cyclophosphamide, Doxorubicin, Paclitaxel and Docetaxel. There does not seem to be any significant adverse effects/ interactions when any of these are used with valtrex, so you can continue using it even if you're given any of the four drugs mentioned above. I posed a question earlier, that got lost in the thread, and then I've been thinking about it and other drugs all day. As I said earlier, I take Valtrex (acyclovir), and I take a bennie every night, (benadryl), and it seems like I am going to be taking quite a bit of ibuprofen. I am unaware of adverse interactions between accutane, valtrex, and/or oral contraceptives, and couldn't find evidence of any on line. Your symtpoms could well be due to accutane along; they arenb't due to valtrex or orth-tricyclen. There are several on-line resources to check drug interactions. it won't have any interactions with your valtrex but topical steroids in the genital area can sometimes trigger herpes to be more active. 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