Definition of antabuse

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  1. Penoplast Well-Known Member

    Definition of antabuse


    Disulfiram (sold under the trade names Antabuse and Antabus) is a drug used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol (drinking alcohol). Disulfiram works by inhibiting the enzyme acetaldehyde dehydrogenase, which means that many of the effects of a "hangover" are felt immediately after alcohol is consumed. "Disulfiram plus alcohol, even small amounts, produce flushing, throbbing in head and neck, throbbing headache, respiratory difficulty, nausea, copious vomiting, sweating, thirst, chest pain, palpitation, dyspnea, hyperventilation, tachycardia, hypotension, syncope, marked uneasiness, weakness, vertigo, blurred vision, and confusion. In severe reactions there may be respiratory depression, cardiovascular collapse, arrhythmias, myocardial infarction, acute congestive heart failure, unconsciousness, convulsions, and death." In the body, alcohol is converted to acetaldehyde, which is then broken down by acetaldehyde dehydrogenase. If the dehydrogenase enzyme is inhibited, acetaldehyde builds up and causes unpleasant effects. Disulfiram should be used in conjunction with counseling and support. Disulfiram has been studied as a possible treatment for cancer Under normal metabolism, alcohol is broken down in the liver by the enzyme alcohol dehydrogenase to acetaldehyde, which is then converted by the enzyme acetaldehyde dehydrogenase to a harmless acetic acid derivative (acetyl coenzyme A). A drug sometimes used in the management of alcoholism, which causes severe nausea and vomiting, sweating, breathlessness, headache and chest pain if any alcohol is taken after it has been given. Disulfiram inhibits the enzyme aldehyde dehydrogenase that breaks down acetaldehyde, a toxic metabolite of alcohol, so that this accumulates. The method is a form of aversion therapy and is not without danger of collapse and death from the toxic effects.

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    Find patient medical information for Antabuse Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Looking for online definition of Antabuse in the Medical Dictionary? Antabuse explanation free. What is Antabuse? Meaning of Antabuse medical term. ANTABUSE. n. the trade name for the drug disulfiram. ANTABUSE "The person was prescribed Antabuse, which is also known as disulfiram. ".

    Disulfiram (tetraethylthiuramdisulfide) was accidentally discovered to combine with ethyl alcohol to produce a noxious effect by Jacobsen and Hald, in Denmark, in 1947. After its therapeutic introduction by Martensen-Larsen in 1948, this chemical compound, with the market name of Antabuse, has been used in the treatment of patients suffering from chronic alcoholism in unknown numbers of thousands. As with any new treatment method, an overly enthusiastic reception occurred, with successes reported in 60% to 80% of the patients so treated and followed for six months to a year. However, the enthusiasm has diminished, until now the recovery rates are about the same as those reported for other therapeutic modalities. Unfortunately, rather than helping those who did not benefit from other techniques, disulfiram works best with those patients who generally do better with any type of treatment. Unlike the other modal verbs, it is only found in the past tense. Therefore, when it is used with do to make negatives and questions, the form of the auxil...

    Definition of antabuse

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    Medical Definition of disulfiram. a compound C10H20N2S4 that causes a severe physiological reaction to alcohol and is used especially in the treatment of alcoholism — Disulfiram sold under the trade names Antabuse and Antabus is a drug used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol drinking alcohol. Define Antabuse. Antabuse synonyms, Antabuse pronunciation, Antabuse translation, English dictionary definition of Antabuse. A trademark for the drug.

     
  5. Pleltak Well-Known Member

    Blepharitis is generally a very uncomfortable eye condition; however, you can typically treat it at home. Castor oil, coconut oil, and tea tree oil are three of the top natural remedies for blepharitis, but there are other effective options. Blepharitis is a condition that involves inflammation of the eyelids. The inflammation is generally caused by an infection that results as a malfunction in the oil glands located at the base of your eyelashes. If you have blepharitis, you’ll likely experience a variety of symptoms including watery or red eyes, a gritty or burning sensation in your eyes, itchy eyelids, greasiness in your eyelids, crusting of your eyelashes, and light sensitivity. We advise at least seeing a doctor to determine the cause and severity of your condition; however, following diagnosis, you can typically treat blepharitis naturally. Castor oil, coconut oil, and tea tree oil are a few of the best natural remedies for blepharitis; however, there are a variety of others as well. The Effect of Low-Dose Doxycycline Therapy in Chronic. - OCuSOFT IF &GGFDU PG -PX %PTF %PYZDZDMJOF 5IFSBQZ JO $ISPOJD. Doxycycline and Blepharitis - Reviews - Treato
     
  6. ahat Well-Known Member

    Metronidazole is indicated in the prophylaxis and treatment of infections in which anaerobic bacteria have been identified or are suspected to be the cause. Anaerobically-infected leg ulcers and pressure sores. The daily dose may be increased to 40 mg/kg, depending on the severity of the infection. 40 mg/kg orally as a single dose or 15 – 30 mg/kg/day divided in 2-3 doses for 7 days; not to exceed 2000 mg/dose Bacterial vaginosis: Adults and children over 10 years: 400mg twice daily for 5-7 days or 2000mg as a single dose for 1 day Amoebiasis: a) Invasive intestinal disease in susceptible subject: 400 mg three times daily for 7 days Children and infants weighing less than 10 kg should receive proportionally smaller dosages. Metronidazole is active against a wide range of pathogenic micro-organisms notably species of Bacteroides, Fusobacteria, Clostridia, Eubacteria, anaerobic cocci and Gardnerella vaginalis. Elderly: Metronidazole is well tolerated by the elderly but a pharmacokinetic study suggests cautious use of high dosage regimens in this age group. It is also active against Trichomonas, Entamoeba histolytica, Giardia lamblia and Balantidium coli. Regular clinical and laboratory monitoring (especially leukocyte count) are advised if administration of metronidazole for more than 10 days is considered to be necessary and patients should be monitored for adverse reactions, such as peripheral or central neuropathy (such as paraesthesia, ataxia, dizziness, convulsive seizures). Metronidazole is indicated in adults and children for the following indications: 1. Metronidazole should be used with caution in patients with active or chronic severe peripheral and central nervous system disease due to the risk of neurological aggravation. The prevention of post-operative infections due to anaerobic bacteria, particularly species of Bacteroides and anaerobic streptococci. The treatment of septicaemia, bacteraemia, peritonitis, brain abscess, necrotising pneumonia, osteomyelitis, puerperal sepsis, pelvic abscess, pelvic cellulitis, and post-operative wound infections from which pathogenic anaerobes have been isolated. Urogenital trichomoniasis in the female (trichomonal vaginitis) and in the male. Bacterial vaginosis (also known as non-specific vaginitis, anaerobic vaginosis or Gardnerella vaginitis). All forms of amoebiasis (intestinal and extra-intestinal disease and that of symptomless cyst passers). The elimination half-life of metronidazole remains unchanged in the presence of renal failure. The usual daily dose is 20-30 mg/kg/day as a single dose or divided into 7.5 mg/kg every 8 hours. Prophylaxis against anaerobic infection: Chiefly in the context of abdominal (especially colorectal) and gynaecological surgery. Bacterial vaginosis treated with metronidazole. Effects on the vaginal. Flagyl 2000 Mg Dose - New Study Recommends 7 Days of Metronidazole for Trichomoniasis
     
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