Antifungal, in the same drug family as ketoconazole and itraconazole. Fluconazole has many advantages over the other antifungal drugs including the option of oral administration. Fluconazole is a first-generation triazole antifungal medication. It differs from earlier azole antifungals (such as ketoconazole) in that its structure contains a triazole ring instead of an imidazole ring. While the imidazole antifungals are mainly used topically, fluconazole and certain other triazole antifungals are preferred when systemic treatment is required because of their improved safety and predictable absorption when administered orally. Fluconazole's spectrum of activity includes most Candida species (but not Candida krusei or Candida glabrata), Cryptococcus neoformans, some dimorphic fungi, and dermatophytes, among others. Common uses include: Fungal resistance to drugs in the azole class tends to occur gradually over the course of prolonged drug therapy, resulting in clinical failure in immunocompromised patients (e.g., patients with advanced HIV receiving treatment for thrush or esophageal Candida infection). albicans, resistance occurs by way of mutations in the ERG11 gene, which codes for 14α-demethylase. These mutations prevent the azole drug from binding, while still allowing binding of the enzyme's natural substrate, lanosterol. glabrata is increasing the rate of efflux of the azole drug from the cell, by both ATP-binding cassette and major facilitator superfamily transporters. Development of resistance to one azole in this way will confer resistance to all drugs in the class. Other gene mutations are also known to contribute to development of resistance. Buy valtrex in australia Zoloft for men Zithromax alcohol interaction Order viagra online paypal Fluconazole. Brand names/Manufacturer Many manufacturers/Brand names. AFUNGIL Senosiain - MEXICO; APO-FLUCONAZOLE Apotex, CANADA. From 1996 to 2012 under the trade name Lipitor. Fluconazole is recommended as a first-line treatment in invasive candidiasis. Trade name of fluconazole is Diflucan, and itraconazole. The key difference between Fluconazole and Itraconazole is that though both are antifungal medications. Read the Patient Information Leaflet if available from your pharmacist before you start taking fluconazole and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth with or without food as directed by your doctor, usually once daily. If you are taking the liquid suspension form of this medication, shake the bottle well before each dose. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. Dosage is based on your medical condition and response to treatment. Generally in children, the dose should not exceed 600 milligrams daily unless directed by the doctor. On December 19, 2018, Pfizer announced a joint merger of their consumer healthcare division with UK pharma giant Glaxo Smith Kline; the British company will maintain a controlling share (listed at 68%). The company develops and produces medicines and vaccines for a wide range of medical disciplines, including immunology, oncology, cardiology, endocrinology, and neurology. Its products include the blockbuster drug Lipitor (atorvastatin), used to lower LDL blood cholesterol; Lyrica (pregabalin) for neuropathic pain and fibromyalgia; Diflucan (fluconazole), an oral antifungal medication; Zithromax (azithromycin), an antibiotic; Viagra (sildenafil) for erectile dysfunction; and Celebrex (also Celebra, celecoxib), an anti-inflammatory drug. was expected to merge with Allergan, Plc to create the Ireland-based "Pfizer plc" in a deal that would have been worth $160 billion. Pfizer was founded in 1849 by German-American Charles Pfizer and his cousin Charles F. They launched the chemicals business Charles Pfizer and Company from a building at the intersection of Harrison Avenue and Bartlett Street in Williamsburg, Brooklyn, where they produced an antiparasitic called santonin. This was an immediate success, although it was the production of citric acid that really kick-started Pfizer's growth in the 1880s. Pfizer continued to buy property to expand its lab and factory on the block bounded by Bartlett Street, Harrison Avenue, Gerry Street, and Flushing Avenue. Pfizer's original administrative headquarters was at 81 Maiden Lane in Manhattan. Fluconazole trade name Fluconazole Oral Uses, Side Effects, Interactions, Pictures., Pfizer - Wikipedia Where can i purchase acyclovir Structure, properties, spectra, suppliers and links for Fluconazole, Diflucan, 86386-73-4. Fluconazole C13H12F2N6O ChemSpider. Difference Between Fluconazole and Itraconazole. Fluconazole - Wikipedia. Products by Trade Name More information about our products is available by clicking on find more below. IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND THE COMPANY/UNDERTAKING Product Identifier Material Name Diflucan fluconazole tablets Trade Name DIFLUCAN Brand Name Contains Dosage Form Manufacturer PriceTk. AFLUZOLE Fluconazole 50mg & 150mg/capsule Capsule Ambee Pharmaceuticals Ltd. 50mg x 30s pack 240.00.