Accutane — the drug that cleared severe acne but was also linked to depression, suicidal thoughts and fetal deformities — is still on the market in its generic form, isotretinoin. How can this be, given that the original drug was discontinued by its manufacturer Hoffmann-La Roche, in part due to lawsuits relating to inflammatory bowel diseases and other issues? With intense patient screening, compliance protocols and careful monitoring, isotretinoin (eye-soh-tret-in-OH-in) can be effective and the risk of terrible side effects can be minimized. Isotretinoin is not without problems, however, so patients need to weigh the risks and the benefits before taking the drug. Here are 9 things you should know about isotretinoin. They can help you gauge whether it is a drug you want to take yourself or have prescribed for your teen to treat severe acne. In 1982, the US Food and Drug Administration () approved the active ingredient isotretinoin for use in treating severe nodular acne, under the brand name Accutane. Our Mission The Friends of the Indian Boundary Prairies is organized exclusively for educational, scientific, and charitable purposes. Our objectives are for the conservation, ecological restoration, ecological stewardship, and preservation of plants, animals, and natural communities, all in the public interest. We wish to promote public awareness, understanding, education, and appreciation of remnant natural areas, of the rare and diverse species that require protected natural remnants for their survival, and of the natural history of these areas. 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Take care that you swallow the capsule whole without breaking, crushing or chewing it unless you have been advised accordingly. Doctors recommend that you swallow the whole tablet/capsules with a glass of water unless it is specified that it can be broken or chewed. NOTE: Use only if prescribed to you and intended for your use. Accutane must be used in a cycle with a 2 month rest period after using the drug. Even during this off period, your acne will continue to get better. And after the 2 month rest period, if you still have severe acne, then inform your doctor who may prescribe a second course of treatment or a longer rest period. Missed Dose It is common for people to forget their dosage times and miss doses. Instead, skip the missed dose and take your next dose at the scheduled time. Accutane (isotretinoin) is a retinoid prescribed for the therapy of extreme nodular pimples in clients that currently attempted other approaches. Prior to you begin taking this medicine, you will should speak to your medical carrier about any sort of contraindications you have such as pregnancy or a history of an allergy to isotretinoin. Make sure you inform your doctor if you are taking minocycline, vitamin A supplements, dexamethasone, demeclocycline, methylprednisolone, prednisone, doxycycline, phenytoin, medications for seizures, or tetracycline, or if you have anorexia nervosa, depression, psychological ailment, history of suicide heart, liver or attempt condition, higher triglyceride levels, asthma, diabetic issues, or weakening of bones. Accutane side effects are possible and can include the adhering to symptoms: voice modifications, dry mouth, completely dry skin, slowed recuperation of cuts, baldness, tiredness, modifications in the nails, aching lips, sweating, winter symptoms, flushing, modifications in skin shade, nosebleeds, and a few other ones. 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